{"id":4823,"date":"2026-10-31T16:15:00","date_gmt":"2026-10-31T09:15:00","guid":{"rendered":"https:\/\/www.nutrispices.com\/?p=4823"},"modified":"2026-11-04T13:03:48","modified_gmt":"2026-11-04T06:03:48","slug":"dien-tich-co-the-chong-lai-vi-khuan-gay-benh-duong-ruot-khong","status":"publish","type":"post","link":"https:\/\/www.nutrispices.com\/vi\/nutrinews\/nutricles\/dien-tich-co-the-chong-lai-vi-khuan-gay-benh-duong-ruot-khong\/","title":{"rendered":"\u0110I\u1ec6N T\u00cdCH C\u00d3 TH\u1ec2 CH\u1ed0NG L\u1ea0I VI KHU\u1ea8N G\u00c2Y B\u1ec6NH \u0110\u01af\u1edcNG RU\u1ed8T KH\u00d4NG ?"},"content":{"rendered":"\n
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Trong dinh d\u01b0\u1ee1ng \u0111\u1ed9ng v\u1eadt, h\u1ea7u h\u1ebft ph\u1ee5 gia kh\u00e1ng khu\u1ea9n trong th\u1ee9c \u0103n ch\u0103n nu\u00f4i \u0111\u1ec1u t\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp l\u00ean m\u1ea7m b\u1ec7nh th\u00f4ng qua c\u00e1c c\u01a1 ch\u1ebf h\u00f3a h\u1ecdc ho\u1eb7c sinh h\u1ecdc. Chitosan th\u00ec kh\u00e1c bi\u1ec7t, n\u00f3 s\u1edf h\u1eefu \u0111\u1eb7c t\u00ednh \u01b0u vi\u1ec7t nh\u1edd v\u00e0o m\u1ed9t \u0111\u1eb7c \u0111i\u1ec3m \u0111\u1ed9c \u0111\u00e1o: \u0111\u00e2y l\u00e0 m\u1ed9t trong s\u1ed1 \u00edt c\u00e1c polysaccharide t\u1ef1 nhi\u00ean c\u00f3 kh\u1ea3 n\u0103ng mang nhi\u1ec1u \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng d\u1ecdc theo c\u1ea5u tr\u00fac ph\u00e2n t\u1eed. \u0110\u1eb7c \u0111i\u1ec3m n\u00e0y cho ph\u00e9p chitosan t\u01b0\u01a1ng t\u00e1c v\u1edbi m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n, \u0111\u1ed3ng th\u1eddi t\u0103ng c\u01b0\u1eddng ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n c\u1ee7a c\u00e1c h\u1ee3p ch\u1ea5t kh\u00e1c, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c axit h\u1eefu c\u01a1.<\/strong><\/p>\n<\/div><\/div>\n\n\n\n

Hi\u1ec3u \u0111\u01b0\u1ee3c l\u00fd do t\u1ea1i sao chitosan mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng v\u00e0 t\u1ea7m quan tr\u1ecdng c\u1ee7a c\u1ea5u tr\u00fac polymer c\u1ee7a chitosan s\u1ebd gi\u00fap gi\u1ea3i th\u00edch c\u00e1ch th\u1ee9c m\u00e0 ch\u1ec9 c\u1ea7n m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf chitosan c\u0169ng c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n.<\/p>\n\n\n\n

\u0110i\u1ec1u g\u00ec khi\u1ebfn chitosan \u0111\u1ed9c \u0111\u00e1o ?<\/strong><\/p>\n\n\n\n

Chitosan \u0111\u01b0\u1ee3c t\u1ea1o ra th\u00f4ng qua qu\u00e1 tr\u00ecnh kh\u1eed acetyl t\u1eeb chitin – m\u1ed9t lo\u1ea1i polysaccharide c\u1ea5u tr\u00fac t\u1ef1 nhi\u00ean c\u00f3 trong v\u1ecf c\u00e1c lo\u00e0i gi\u00e1p x\u00e1c, c\u00f4n tr\u00f9ng v\u00e0 n\u1ea5m.<\/p>\n\n\n\n

Kh\u00e1c v\u1edbi cellulose, tinh b\u1ed9t v\u00e0 h\u1ea7u h\u1ebft c\u00e1c polysaccharide t\u1ef1 nhi\u00ean kh\u00e1c, chitosan ch\u1ee9a nhi\u1ec1u nh\u00f3m amino t\u1ef1 do (\u2013NH\u2082). Trong m\u00f4i tr\u01b0\u1eddng axit, c\u00e1c nh\u00f3m n\u00e0y b\u1ecb proton h\u00f3a (tr\u1edf th\u00e0nh \u2013NH\u2083\u207a), khi\u1ebfn ph\u00e2n t\u1eed mang nhi\u1ec1u \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng. Hi\u1ec3u \u0111\u01b0\u1ee3c l\u00fd do t\u1ea1i sao chitosan mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng v\u00e0 t\u1ea7m quan tr\u1ecdng c\u1ee7a c\u1ea5u tr\u00fac polymer c\u1ee7a chitosan s\u1ebd gi\u00fap gi\u1ea3i th\u00edch c\u00e1ch th\u1ee9c m\u00e0 ch\u1ec9 c\u1ea7n m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf chitosan c\u0169ng c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n.<\/p>\n\n\n\n

\u0110\u1eb7c \u0111i\u1ec3m n\u00e0y \u0111\u1eb7c bi\u1ec7t quan tr\u1ecdng v\u00ec b\u1ec1 m\u1eb7t vi khu\u1ea9n th\u01b0\u1eddng mang \u0111i\u1ec7n t\u00edch \u00e2m do s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a c\u00e1c phospholipid, protein v\u00e0 nh\u1eefng th\u00e0nh ph\u1ea7n c\u1ea5u tr\u00fac kh\u00e1c.<\/p>\n\n\n\n

C\u00e1c \u0111i\u1ec7n t\u00edch tr\u00e1i d\u1ea5u s\u1ebd h\u00fat nhau. Do \u0111\u00f3, c\u00e1c ph\u00e2n t\u1eed chitosan mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng s\u1ebd t\u1ef1 nhi\u00ean b\u1ecb thu h\u00fat v\u1ec1 ph\u00eda b\u1ec1 m\u1eb7t vi khu\u1ea9n.<\/p>\n\n\n

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Nh\u01b0ng l\u1ee3i th\u1ebf th\u1ef1c s\u1ef1 c\u1ee7a chitosan kh\u00f4ng ch\u1ec9 \u0111\u01a1n thu\u1ea7n n\u1eb1m \u1edf \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng c\u1ee7a n\u00f3. \u0110\u00f3 l\u00e0 vi\u1ec7c c\u00e1c \u0111i\u1ec7n t\u00edch n\u00e0y \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed1 d\u1ecdc theo m\u1ed9t chu\u1ed7i polymer d\u00e0i.<\/p>\n\n\n\n

T\u1ea1i sao polymer l\u1ea1i quan tr\u1ecdng \u0111\u1ebfn v\u1eady?<\/strong><\/p>\n\n\n\n

Polyme l\u00e0 m\u1ed9t ph\u00e2n t\u1eed l\u1edbn bao g\u1ed3m nhi\u1ec1u \u0111\u01a1n v\u1ecb l\u1eb7p l\u1ea1i k\u1ebft n\u1ed1i v\u1edbi nhau. Trong chitosan, m\u1ed7i \u0111\u01a1n v\u1ecb c\u00f3 kh\u1ea3 n\u0103ng mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng.<\/p>\n\n\n\n

Kh\u00e1c v\u1edbi m\u1ed9t ph\u00e2n t\u1eed nh\u1ecf mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng ch\u1ec9 t\u01b0\u01a1ng t\u00e1c t\u1ea1i m\u1ed9t v\u1ecb tr\u00ed duy nh\u1ea5t, m\u1ed9t ph\u00e2n t\u1eed polyme chitosan c\u00f3 th\u1ec3 thi\u1ebft l\u1eadp \u0111\u1ed3ng th\u1eddi nhi\u1ec1u t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n v\u1edbi c\u00f9ng m\u1ed9t b\u1ec1 m\u1eb7t vi khu\u1ea9n.<\/p>\n\n\n\n

Hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 li\u00ean k\u1ebft \u0111a h\u00f3a tr\u1ecb (multivalent binding), t\u1ea1o ra s\u1ef1 g\u1eafn k\u1ebft m\u1ea1nh m\u1ebd h\u01a1n nhi\u1ec1u so v\u1edbi m\u1ed9t t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n \u0111\u01a1n l\u1ebb.<\/p>\n\n\n\n

Khi \u0111\u00e3 g\u1eafn k\u1ebft, polyme c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi nhi\u1ec1u v\u1ecb tr\u00ed mang \u0111i\u1ec7n t\u00edch \u00e2m, l\u00e0m x\u00e1o tr\u1ed9n c\u1ea5u tr\u00fac l\u1edbp v\u1ecf vi khu\u1ea9n. T\u00f9y thu\u1ed9c v\u00e0o tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed v\u00e0 c\u1ea5u tr\u00fac, chitosan c\u00f2n c\u00f3 th\u1ec3 k\u1ebft n\u1ed1i c\u00e1c t\u1ebf b\u00e0o vi khu\u1ea9n l\u1ea1i v\u1edbi nhau, th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh k\u1ebft t\u1ee5.<\/p>\n\n\n\n

C\u00e1c t\u01b0\u01a1ng t\u00e1c n\u00e0y t\u1ea1o ra m\u1ed9t s\u1ed1 t\u00e1c \u0111\u1ed9ng sinh h\u1ecdc:<\/p>\n\n\n\n

    \n
  • T\u1ed5n th\u01b0\u01a1ng m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n v\u00e0 t\u0103ng t\u00ednh th\u1ea5m.<\/li>\n\n\n\n
  • R\u00f2 r\u1ec9 c\u00e1c th\u00e0nh ph\u1ea7n n\u1ed9i b\u00e0o v\u00e0 g\u00e2y c\u1ea3n tr\u1edf trao \u0111\u1ed5i ch\u1ea5t c\u1ee7a vi khu\u1ea9n.<\/li>\n\n\n\n
  • K\u1ebft t\u1ee5 c\u00e1c t\u1ebf b\u00e0o vi khu\u1ea9n, c\u00f3 kh\u1ea3 n\u0103ng t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho vi\u1ec7c lo\u1ea1i b\u1ecf ch\u00fang.<\/li>\n\n\n\n
  • Gi\u1ea3m kh\u1ea3 n\u0103ng b\u00e1m d\u00ednh c\u1ee7a vi khu\u1ea9n v\u00e0 h\u00ecnh th\u00e0nh m\u00e0ng sinh h\u1ecdc trong m\u1ed9t s\u1ed1 \u0111i\u1ec1u ki\u1ec7n nh\u1ea5t \u0111\u1ecbnh.<\/li>\n<\/ul>\n\n\n\n

    B\u1ec1 m\u1eb7t vi khu\u1ea9n th\u01b0\u1eddng mang \u0111i\u1ec7n t\u00edch \u00e2m m\u1ea1nh h\u01a1n so v\u1edbi m\u00e0ng ngo\u00e0i c\u1ee7a c\u00e1c t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 ru\u1ed9t (t\u1ebf b\u00e0o ru\u1ed9t) \u2013 v\u1ed1n ch\u1ee9a ch\u1ee7 y\u1ebfu l\u00e0 c\u00e1c phospholipid trung t\u00ednh v\u00e0 cholesterol.<\/p>\n\n\n\n

    Do \u0111\u00f3, chitosan t\u01b0\u01a1ng t\u00e1c \u01b0u ti\u00ean v\u1edbi b\u1ec1 m\u1eb7t vi khu\u1ea9n, t\u1ea1o n\u00ean m\u1ed9t m\u1ee9c \u0111\u1ed9 ch\u1ecdn l\u1ecdc nh\u1ea5t \u0111\u1ecbnh trong ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n.<\/p>\n\n\n\n

    Chitosan v\u00e0 c\u00e1c axit h\u1eefu c\u01a1: S\u1ef1 hi\u1ec7p \u0111\u1ed3ng mang t\u00ednh x\u00fac t\u00e1c<\/strong><\/p>\n\n\n\n

    C\u00e1c axit h\u1eefu c\u01a1, \u0111\u1eb7c bi\u1ec7t l\u00e0 axit formic, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i \u0111\u1ec3 ki\u1ec3m so\u00e1t s\u1ef1 t\u0103ng sinh c\u1ee7a vi khu\u1ea9n trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n\n\n\n

    Ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n c\u1ee7a ch\u00fang ph\u1ee5 thu\u1ed9c m\u1ed9t ph\u1ea7n v\u00e0o kh\u1ea3 n\u0103ng th\u00e2m nh\u1eadp qua m\u00e0ng vi khu\u1ea9n \u1edf d\u1ea1ng kh\u00f4ng ph\u00e2n ly.<\/p>\n\n\n\n

    Khi \u0111\u00e3 v\u00e0o b\u00ean trong t\u1ebf b\u00e0o vi khu\u1ea9n, c\u00e1c axit h\u1eefu c\u01a1 s\u1ebd ph\u00e2n ly, gi\u1ea3i ph\u00f3ng c\u00e1c proton v\u00e0 anion. Qu\u00e1 tr\u00ecnh n\u00e0y l\u00e0m gi\u00e1n \u0111o\u1ea1n c\u01a1 ch\u1ebf \u0111i\u1ec1u h\u00f2a pH n\u1ed9i b\u00e0o, bu\u1ed9c vi khu\u1ea9n ph\u1ea3i ti\u00eau t\u1ed1n n\u0103ng l\u01b0\u1ee3ng \u0111\u1ec3 kh\u00f4i ph\u1ee5c tr\u1ea1ng th\u00e1i c\u00e2n b\u1eb1ng sinh l\u00fd c\u1ee7a ch\u00ednh n\u00f3.<\/p>\n\n\n\n

    Chitosan c\u00f3 th\u1ec3 c\u1ee7ng c\u1ed1 c\u01a1 ch\u1ebf n\u00e0y b\u1eb1ng c\u00e1ch t\u00e1c \u0111\u1ed9ng tr\u01b0\u1edbc h\u1ebft l\u00ean m\u00e0ng vi khu\u1ea9n.<\/p>\n\n\n\n

    Th\u00f4ng qua nhi\u1ec1u t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n, chitosan l\u00e0m m\u1ea5t \u1ed5n \u0111\u1ecbnh l\u1edbp v\u1ecf vi khu\u1ea9n v\u00e0 t\u0103ng t\u00ednh th\u1ea5m c\u1ee7a m\u00e0ng. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c axit h\u1eefu c\u01a1, \u0111\u1ed3ng th\u1eddi c\u1ee7ng c\u1ed1 t\u00e1c d\u1ee5ng kh\u00e1ng khu\u1ea9n c\u1ee7a ch\u00fang b\u00ean trong t\u1ebf b\u00e0o.<\/p>\n\n\n\n

    Do \u0111\u00f3, s\u1ef1 k\u1ebft h\u1ee3p n\u00e0y bao g\u1ed3m hai c\u01a1 ch\u1ebf b\u1ed5 tr\u1ee3 cho nhau:<\/p>\n\n\n\n

      \n
    1. Chitosan b\u00e1m v\u00e0 l\u00e0m m\u1ea5t \u1ed5n \u0111\u1ecbnh m\u00e0ng vi khu\u1ea9n.<\/li>\n\n\n\n
    2. C\u00e1c axit h\u1eefu c\u01a1 th\u00e2m nh\u1eadp v\u00e0o vi khu\u1ea9n v\u00e0 ph\u00e1 v\u1ee1 qu\u00e1 tr\u00ecnh trao \u0111\u1ed5i ch\u1ea5t b\u00ean trong ch\u00fang.<\/li>\n<\/ol>\n\n\n
      \n
      \"\"<\/figure>\n<\/div>\n\n\n

      T\u00e1c \u0111\u1ed9ng b\u1ed5 tr\u1ee3 n\u00e0y c\u00f3 th\u1ec3 t\u1ea1o ra hi\u1ec7u \u1ee9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 x\u00fac t\u00e1c, qua \u0111\u00f3 c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u1ee9c ch\u1ebf t\u1ed1i thi\u1ec3u (MIC) c\u1ee7a c\u00e1c axit h\u1eefu c\u01a1 c\u1ea7n thi\u1ebft \u0111\u1ec3 ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a vi khu\u1ea9n.<\/p>\n\n\n\n

      S\u1ef1 t\u0103ng c\u01b0\u1eddng t\u00e1c d\u1ee5ng n\u00e0y c\u00f3 th\u1ec3 x\u1ea3y ra \u0111\u1ed1i v\u1edbi c\u1ea3 vi khu\u1ea9n gram \u00e2m (nh\u01b0 E. coli<\/em> v\u00e0 Salmonella<\/em>) l\u1eabn vi khu\u1ea9n gram d\u01b0\u01a1ng (nh\u01b0 Clostridium perfringens<\/em>).<\/p>\n\n\n\n

      Do \u0111\u00f3, vi\u1ec7c k\u1ebft h\u1ee3p chitosan \u1edf li\u1ec1u l\u01b0\u1ee3ng t\u01b0\u01a1ng \u0111\u1ed1i th\u1ea5p v\u1edbi c\u00e1c axit h\u1eefu c\u01a1 c\u00f3 th\u1ec3 mang l\u1ea1i ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n m\u1ea1nh m\u1ebd h\u01a1n so v\u1edbi khi s\u1eed d\u1ee5ng ri\u00eang l\u1ebb t\u1eebng th\u00e0nh ph\u1ea7n. Ph\u01b0\u01a1ng ph\u00e1p n\u00e0y c\u0169ng c\u00f3 th\u1ec3 m\u1edf r\u1ed9ng ph\u1ed5 kh\u00e1ng khu\u1ea9n, gi\u00fap \u0111\u1ea1t hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi c\u1ea3 nh\u1eefng ch\u1ee7ng vi khu\u1ea9n \u00edt nh\u1ea1y c\u1ea3m h\u01a1n.<\/p>\n\n\n\n

      M\u1ed9t s\u1ef1 hi\u1ec7p \u0111\u1ed3ng t\u01b0\u01a1ng t\u1ef1 c\u00f3 th\u1ec3 x\u1ea3y ra v\u1edbi k\u1ebdm oxit, v\u00ec qu\u00e1 tr\u00ecnh g\u00e2y m\u1ea5t \u1ed5n \u0111\u1ecbnh m\u00e0ng t\u1ebf b\u00e0o do chitosan t\u1ea1o ra c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u1ed9 nh\u1ea1y c\u1ea3m c\u1ee7a vi khu\u1ea9n \u0111\u1ed1i v\u1edbi c\u00e1c ion k\u1ebdm. S\u1ef1 k\u1ebft h\u1ee3p n\u00e0y \u0111\u1eb7c bi\u1ec7t \u0111\u00e1ng ch\u00fa \u00fd trong vi\u1ec7c ki\u1ec3m so\u00e1t vi khu\u1ea9n E. coli<\/em> g\u00e2y b\u1ec7nh tr\u00ean heo con sau cai s\u1eefa.<\/p>\n\n\n\n

      Chitosan kh\u00e1c bi\u1ec7t so v\u1edbi c\u00e1c ch\u1ea5t ph\u1ee5 gia th\u1ee9c \u0103n ch\u0103n nu\u00f4i th\u00f4ng th\u01b0\u1eddng nh\u1edd c\u1ea5u tr\u00fac chu\u1ed7i polymer d\u00e0i mang nhi\u1ec1u \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng, cho ph\u00e9p n\u00f3 t\u01b0\u01a1ng t\u00e1c \u0111\u1ed3ng th\u1eddi v\u1edbi b\u1ec1 m\u1eb7t c\u1ee7a vi khu\u1ea9n.<\/p>\n\n\n\n

      Do \u0111\u00f3, gi\u00e1 tr\u1ecb l\u1edbn nh\u1ea5t c\u1ee7a chitosan c\u00f3 l\u1ebd kh\u00f4ng n\u1eb1m \u1edf vi\u1ec7c thay th\u1ebf c\u00e1c h\u1ee3p ch\u1ea5t kh\u00e1ng khu\u1ea9n hi\u1ec7n c\u00f3, m\u00e0 \u1edf kh\u1ea3 n\u0103ng n\u00e2ng cao hi\u1ec7u qu\u1ea3 c\u1ee7a ch\u00fang ngay c\u1ea3 khi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng v\u1edbi h\u00e0m l\u01b0\u1ee3ng t\u01b0\u01a1ng \u0111\u1ed1i th\u1ea5p.<\/p>\n\n\n\n

      B\u1eb1ng c\u00e1ch l\u00e0m suy y\u1ebfu m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n, chitosan c\u00f3 th\u1ec3 t\u0103ng c\u01b0\u1eddng t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c axit h\u1eefu c\u01a1 v\u00e0 k\u1ebdm oxit, t\u1eeb \u0111\u00f3 c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u1ee9c ch\u1ebf t\u1ed1i thi\u1ec3u (MIC) c\u1ea7n thi\u1ebft \u0111\u1ec3 ki\u1ec3m so\u00e1t vi khu\u1ea9n hi\u1ec7u qu\u1ea3, \u0111\u1ed3ng th\u1eddi cung c\u1ea5p cho c\u00e1c chuy\u00ean gia dinh d\u01b0\u1ee1ng th\u00eam m\u1ed9t c\u00f4ng c\u1ee5 \u0111\u1ec3 c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe \u0111\u01b0\u1eddng ru\u1ed9t.<\/p>\n","protected":false},"excerpt":{"rendered":"

      Trong dinh d\u01b0\u1ee1ng \u0111\u1ed9ng v\u1eadt, h\u1ea7u h\u1ebft ph\u1ee5 gia kh\u00e1ng khu\u1ea9n trong th\u1ee9c \u0103n ch\u0103n nu\u00f4i \u0111\u1ec1u t\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp l\u00ean m\u1ea7m b\u1ec7nh th\u00f4ng qua c\u00e1c c\u01a1 ch\u1ebf h\u00f3a h\u1ecdc ho\u1eb7c sinh h\u1ecdc. Chitosan th\u00ec kh\u00e1c bi\u1ec7t, n\u00f3 s\u1edf h\u1eefu \u0111\u1eb7c t\u00ednh \u01b0u vi\u1ec7t nh\u1edd v\u00e0o m\u1ed9t \u0111\u1eb7c \u0111i\u1ec3m \u0111\u1ed9c \u0111\u00e1o: \u0111\u00e2y l\u00e0 m\u1ed9t trong s\u1ed1 \u00edt c\u00e1c polysaccharide t\u1ef1 nhi\u00ean c\u00f3 kh\u1ea3 n\u0103ng mang nhi\u1ec1u \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng d\u1ecdc theo c\u1ea5u tr\u00fac ph\u00e2n t\u1eed. \u0110\u1eb7c \u0111i\u1ec3m n\u00e0y cho ph\u00e9p chitosan t\u01b0\u01a1ng t\u00e1c v\u1edbi m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n, \u0111\u1ed3ng th\u1eddi t\u0103ng c\u01b0\u1eddng ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n c\u1ee7a c\u00e1c h\u1ee3p ch\u1ea5t kh\u00e1c, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c axit h\u1eefu c\u01a1. Hi\u1ec3u \u0111\u01b0\u1ee3c l\u00fd do t\u1ea1i sao chitosan mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng v\u00e0 t\u1ea7m quan tr\u1ecdng c\u1ee7a c\u1ea5u tr\u00fac polymer c\u1ee7a chitosan s\u1ebd gi\u00fap gi\u1ea3i th\u00edch c\u00e1ch th\u1ee9c m\u00e0 ch\u1ec9 c\u1ea7n m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf chitosan c\u0169ng c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n. \u0110i\u1ec1u g\u00ec khi\u1ebfn chitosan \u0111\u1ed9c \u0111\u00e1o ? Chitosan \u0111\u01b0\u1ee3c t\u1ea1o ra th\u00f4ng qua qu\u00e1 tr\u00ecnh kh\u1eed acetyl t\u1eeb chitin – m\u1ed9t lo\u1ea1i polysaccharide c\u1ea5u tr\u00fac t\u1ef1 nhi\u00ean c\u00f3 trong v\u1ecf c\u00e1c lo\u00e0i gi\u00e1p x\u00e1c, c\u00f4n tr\u00f9ng v\u00e0 n\u1ea5m. Kh\u00e1c v\u1edbi cellulose, tinh b\u1ed9t v\u00e0 h\u1ea7u h\u1ebft c\u00e1c polysaccharide t\u1ef1 nhi\u00ean kh\u00e1c, chitosan ch\u1ee9a nhi\u1ec1u nh\u00f3m amino t\u1ef1 do (\u2013NH\u2082). Trong m\u00f4i tr\u01b0\u1eddng axit, c\u00e1c nh\u00f3m n\u00e0y b\u1ecb proton h\u00f3a (tr\u1edf th\u00e0nh \u2013NH\u2083\u207a), khi\u1ebfn ph\u00e2n t\u1eed mang nhi\u1ec1u \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng. Hi\u1ec3u \u0111\u01b0\u1ee3c l\u00fd do t\u1ea1i sao chitosan mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng v\u00e0 t\u1ea7m quan tr\u1ecdng c\u1ee7a c\u1ea5u tr\u00fac polymer c\u1ee7a chitosan s\u1ebd gi\u00fap gi\u1ea3i th\u00edch c\u00e1ch th\u1ee9c m\u00e0 ch\u1ec9 c\u1ea7n m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf chitosan c\u0169ng c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 hi\u1ec7u qu\u1ea3 kh\u00e1ng khu\u1ea9n. \u0110\u1eb7c \u0111i\u1ec3m n\u00e0y \u0111\u1eb7c bi\u1ec7t quan tr\u1ecdng v\u00ec b\u1ec1 m\u1eb7t vi khu\u1ea9n th\u01b0\u1eddng mang \u0111i\u1ec7n t\u00edch \u00e2m do s\u1ef1 hi\u1ec7n<\/p>\n","protected":false},"author":4,"featured_media":4821,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[36],"tags":[],"class_list":["post-4823","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nutricles-vi"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/posts\/4823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/comments?post=4823"}],"version-history":[{"count":2,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/posts\/4823\/revisions"}],"predecessor-version":[{"id":4827,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/posts\/4823\/revisions\/4827"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/media\/4821"}],"wp:attachment":[{"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/media?parent=4823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/categories?post=4823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nutrispices.com\/vi\/wp-json\/wp\/v2\/tags?post=4823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}